Gb263t
WebBrief Summary: This is a Phase 1/2 study of GB263T in participants with advanced NSCLC and other solid tumor. The study will consist of a dose-escalation and expansion stage to … WebJun 15, 2024 · GB263T is a novel EGFR/cMET/cMET tri-specific antibody with enhanced ADCC function. The current study has demonstrated GB263T exhibited robust anti-tumor …
Gb263t
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WebWe are very pleased to announce that GB263T, the world's first EGFR/cMET/cMET tri-specific antibody targeting EGFR and two different epitopes of cMET, has… WebAug 5, 2024 · Brief Summary. This is a Phase 1/2 study of GB263T in participants with advanced NSCLC and other solid tumor. The study will consist of a dose-escalation and …
WebCharacterization of GB263T, a tri-specific antibody against EGFR/cMET/cMET for NSCLC (AACR 2024) Amivantamab, a bispecific antibody to EGFR/c-Met has shown that concurrent inhibition of EGFR and c-Met can overcome resistance of EGFR-TKIs and improve patient outcomes. GB263T is a novel tri-specific antibody that exhibited robust anti-tumor activity. WebMay 18, 2024 · 因此,gb263t具有高度差异化的设计,表现出多种作用机制,可同时抑制原发性及继发性egfr突变及cmet信号通路。 临床前研究表明,与 Amivantamab(JNJ-372) …
Web研究报告节选: 6.16.嘉和生物:杰洛利单抗获批在即,多个药物处于 3 期临床 在研管线方面:pd-1 单抗杰洛利单抗处于 bla 阶段,预计 2024 年获批,公司将开启商业化;此外,cdk4/6 抑制剂、cd20 单抗、her2 单抗均处于 3 期临床。 WebJul 27, 2024 · GB263T is the world's first EGFR/cMET/cMET tri-specific antibody targeting EGFR and two different epitopes of cMET and has been rationally designed with the goal of improving safety and efficacy. Thus, GB263T is a highly differentiated tri-specific antib ody that exhibits multiple mechanisms of action to inhibit primary and secondary EGFR ...
WebGB263T NSCL C 全球 GB26 4 全球 類別 3 期 2 期 1 期 2LHR+/HER2-BC EGFR-突變 NSCLC (與呋喹替尼聯用) 實體瘤 HER2+ 1L/2L+mBC 胃腸癌 EGFR×c-Met×c-Met (1) Claudin18.2×CD3 G1 Therapeutics 商業權利 炎性疾病
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