Bapta-am的作用
WebBAPTA-AM is the acetoxymethylester of the calcium chelator BAPTA and has demonstrated efficacy in several animal models of cerebral ischemia. This paper … WebBAPTA-AM is a selective calcium chelator [1]. Ca2+ is one of the most ubiquitous and versatile intracellular signaling molecules that control numerous cellular processes such as neurotransmitter release, contraction of all muscle cell types and fertilization [4]. BAPTA-AM is a selective and membrane permeable calcium chelator.
Bapta-am的作用
Did you know?
WebCa 2+ signaling events in many different cell types are tracked with fluorescent Ca 2+ indicators, such as Fluo-4, Rhod-2, and Fura-2, and can be inhibited with the Ca 2+ chelator BAPTA. Smith et al. found that … WebBAPTA is a calcium-selective chelator developed by Dr. Tsien. It has logK Ca =6.97 and logK Mg =1.77. The basic chelating unit resembles that of EGTA, but the two aliphatic nitrogen atoms are replaced by aromatic nitrogen. Thus, BAPTA is not protonated at physiological pH. BAPTA possesses pKa 3 =5.47 and pKa 4 =6.36.
Webbapta-am是一种众所周知的膜渗透性ca2 +螯合剂,通过减轻细胞内钙过载来防止细胞损伤,使用mtt测定法研究了bapta-am的ic50值。在乳腺癌4t1细胞系中,bapta-am的ic50值被 … WebMembrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator …
http://www.ibp.cas.cn/kyjz/zxdt/202409/t20240930_6519085.html WebBAPTA-AM is a well-known membrane permeable Ca2+ chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50 s of 1.3 μM, …
http://www.activeinhibitor.com/xw/80.html
WebJan 4, 2024 · 细胞实验. 通过在10μMBAPTA/ AM处理后24小时或48小时测量从受损细胞释放到沐浴培养基中的乳酸脱氢酶(LDH)来定量估计神经元损伤。. 通过用神经元特异性烯 … one hundredth of an israeli shekelWebBAPTA-AM inhibits neuronal Ca 2+ -activated K + channel currents, and up-regulates the decreased cardiac sodium current (INa) density by chelating intracellular Ca 2+ [1]. … one hundredth of a literWebBAPTA 是一种选择性的钙离子螯合剂。BAPTA 作为钙离子指示剂,对镁离子和钙离子有较高的选择性。BAPTA 被广泛用作细胞内缓冲液,用于研究通过质膜 Ca2+ 透性通道从细 … is being in a sorority worth itWebNov 23, 2006 · 1、原子结构不同. 乙二胺四乙酸及其二钠盐,简称EDTA ,乙二醇二乙醚二胺四乙酸简称EGTA。. EDTA能通过两个N原子,四个O原子共六个配位原子与金属离子结 … one hundredth of a millimeterWebbapta am是一种选择性的钙螯合剂,对ca2+的选择性比mg2+高100倍以上。bapta am是bapta(cat#:km0035)的乙酰氧基甲酯衍生物,具细胞膜渗透性,能用来控制胞 … one hundredth of an inchone hundredth of a liter is equal to oneWebThese results revealed that BAPTA-AM inhibit osteoclastogenic ability of BMMs via suppressing the increase of [Ca(2+)](i) which lead to inhibit RANKL-induced the … one hundredth of an hour